Biotin Picolyl Azide

Biotin Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.

The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Biotin Picolyl Azide, 100 mg
100mg In stock
Regular Price:$1,263.00
On Sale:

Product Type: Small Molecule
Chemical Formula: C27H42N8O7S
CAS number: N/A
Molecular Weight: 622.74
Variant MPN: 1167
Format: Off-white to slightly orange amorphous solid
Purity: >95% (HPLC)
Solubility: DMSO, DMF
Storage: -20C. Desiccate
Shipped: Ambient

  1. Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem., 25(4): 698-706.
  2. Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,. 51(24): 5852–5856.

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