Biotin Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.
The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.
|Off-white to slightly orange amorphous solid
If you publish research with this product, please let us know so we can cite your paper.