Cy7 Picolyl Azide
Cy7 Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.
The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.
Cy7 Picolyl Azide incorporates a copper-chelating group to the azide structure to allow co-diffusion and concentrate copper at the reaction site.
The picolyl azide effect is so strong that it more than compensate for the effect of omitting THPTA ligand or decreasing the Cu concentration from 100 μm to 10 μm. In addition Biotin Picolyl Azide can be used under classic copper-catalyzed click reactions with dramatically increased efficiency.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Small Molecule |
| CAS number: | N/A |
| Molecular Weight: | 1175.34 |
| Extinction Coefficient: | 255000 |
| Variant MPN: | 1183 |
| Format: | Dark green solid |
| Purity: | >95% (HPLC) |
| Solubility: | Water, DMSO, DMF, MeOH |
| Spectral Information: | Abs/Em = 753/775 nm |
| Storage: | -20C. Desiccate |
| Shipped: | Ambient |
Documentation
References
- Jiang H, Zheng T, Lopez-Aguilar A, Feng L, Kopp F, Marlow FL, Wu P. Monitoring dynamic glycosylation in vivo using supersensitive click chemistry. Bioconjug Chem. 2014 Apr 16;25(4):698-706.
- Uttamapinant C, Tangpeerachaikul A, Grecian S, Clarke S, Singh U, Slade P, Gee KR, Ting AY. Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labeling. Angew Chem Int Ed Engl. 2012 Jun 11;51(24):5852-6.
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