Human Pancreatic Duct Epithelial Cell Line (H6c7)

Human Pancreatic Duct Epithelial Cell Line (H6c7)

H6c7 is an immortalized epithelial cell line derived from normal human pancreatic duct epithelial (HPDE) cells. This cell line is an attractive model for human pancreatic duct cell carcinogenesis studies.

Highlights

  • Demonstrate near normal genotype and phenotype of HPDE cells
  • Display copy number of p16INK4A gene, wild type p53 and KRAS genes
  • Morphologically similar to the primary HPDE cells, grow anchorage-dependently and do not form tumors in scid mice
  • Growth remains inhibited by transforming growth factor (TGF)-beta 1

From the laboratory of Ming-Sound Tsao, MD, FRCPC, University Health Network, Canada.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
ECA001-FP
Human Pancreatic Duct Epithelial Cell Line (H6c7), 1 Vial (Non-Profit)
1 vial In stock
Regular Price:$925.00
On Sale:

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Specifications

Product Type: Cell Line
Name: H6C7
Cell Type: Epithelial
Accession ID: CVCL_0P38
Organism: Human
Source: Pancreatic duct
Morphology: Epithelial
Biosafety Level: BSL2
Subculturing: 1:4 split (see PDF Suggested Protocol)
Growth Conditions: Keratinocyte SFM, + EGF + bovine pituitary extract (Invitrogen Cat#:17005042) supplemented with 1x antibiotic-antimycotic (Gibco Cat#15240- 062);
(See PDF Suggested Protocol)
Cryopreservation: Growth medium plus 10% DMSO
Mycoplasma Tested: Yes
Storage: Liquid nitrogen
Shipped: Dry ice

Documentation

PDF Suggested Protocol

Provider
From the laboratory of Ming-Sound Tsao, MD, FRCPC, University Health Network, Canada.
References
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