Violacein
Violacein, isolated from a non-pathogenic, psychrotolerant microorganism.
Violacein is a natural purple pigment found in microorganisms living in unique environments, from the tropic to glaciers. It acts as a natural defense system against other organisms, including amoebas, bacteria and parasites. In addition to the pigment properties of violacein, it has been demonstrated that this bio-compound exhibits several other interesting properties such as antimicrobial, antiparasitic and antitumoral activities.
Violacein, isolated from a non-pathogenic, psychrotolerant microorganism.
Violacein is a natural purple pigment found in microorganisms living in unique environments, from the tropic to glaciers. It acts as a natural defense system against other organisms, including amoebas, bacteria and parasites. In addition to the pigment properties of violacein, it has been demonstrated that this bio-compound exhibits several other interesting properties such as antimicrobial, antiparasitic and antitumoral activities.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
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Specifications
| Product Type: | Small Molecule |
| Name: | Violacein |
| Chemical Formula: | C20H13N3O3 |
| CAS number: | 548-54-9 |
| Molecular Weight: | 343.34 g/mol |
| Format: | Lyophilized powder; deep violet |
| Purity: | > 95% |
| Solubility: | methanol (stir) |
| Storage: | 2-8°C, avoid light exposure (up to 2 years) |
| Shipped: | Cold packs |
Documentation
References
- Yuan Lua, et al. (2009) Production of violet pigment by a newly isolated psychrotrophic bacterium from a glacier in Xinjiang, China. Biochemical Engineering Journal; 43: 135141.
- Pantanella, et al. (2007) Violacein and biofilm production in Janthinobacterium lividum. Journal of Applied Microbiology: 102; 992999.
- Nelson Durán, et al. (2007) Violacein: properties and biological activities. Biotechnol. Appl. Biochem.; 48: 127133.
- Duran M, Ponezi AN, Faljoni-Alario A, Teixeira MFS, Justo GZ, Duran N (2012) Potential applications of violacein: a microbial pigment. Med Chem Res 21:1524-1532.
- Cazoto LL, Martins D, Ribeiro MG, Duran N, Nakazato G (2011) Antibacterial activity of violacein against Staphylococcus aureus isolated from Bovine Mastitis. J. antibiot (Tokyo) 64:395-397.
- Nakamura Y, Asada C, Sawada T (2003) Production of antibacterial violet pigment by psychrotrophic bacterium RT102 strain. Biotechnol Bioprocess Eng 8:37-40.
- Lopes SCP, Blanco YC, Justo GZ, Nogueira PA, Rodrigues FLS, Goelnitz U, Wunderlich G, Facchini G, Brocchi M, Duran N, Costa FTM (2009) Violacein extracted from Chromobacterium violaceum inhibits Plasmodium growth in vitro and in vivo. Antimocrob Agents Chemother 53:2149-2152.
- Deines P, Matz C, Jurgens K (2009) Toxicity of violacein-producing bacteria fed to bacterivorous freshwater plankton. Limnol Oceanogr 54:1343-1352.
- Ferreira CV, Bos CL, Versreeg HH, Justo GZ, Duran N, Peppelenbosch MP (2004) Molecular mechanism of violacein-mediated human leukemia cell death. Blood 104:1459-1464
- Bromberg N, Dreyfuss JL, Regatieri CV, Palladino MV, Duran N, Nader HB, Haun M, Justo GZ (2010) Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor. Chem Biol Interact 186:43-52.
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