pGEX-5X-1-Znf131 Plasmids
These plasmids were derived using the pGEX-5X-1 plasmid as the backbone and contain the cDNA encoding for full-length, as well as various regions of the transcription factor Znf131.
Zinc finger protein, 131 plays a role during development and organogenesis as well as in the function of the adult central nervous system. In addition, it has been shown to be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.
Kaiso, a transcription factor was first identified as a specific binding partner for the catenin p120ctn, which is aberrantly expressed or absent in human breast, colon and skin cancers. Kaiso is also a member of the POZ-zinc finger family of transcription factors implicated as oncoproteins or tumor suppressors, and currently it is the only known POZ protein with bi-modal DNA-binding and transcriptional repression activity.
From the laboratory of Juliet M. Daniel, PhD, McMaster Univeristy
Part of The Investigator's Annexe program.
These plasmids were derived using the pGEX-5X-1 plasmid as the backbone and contain the cDNA encoding for full-length, as well as various regions of the transcription factor Znf131.
Zinc finger protein, 131 plays a role during development and organogenesis as well as in the function of the adult central nervous system. In addition, it has been shown to be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.
Kaiso, a transcription factor was first identified as a specific binding partner for the catenin p120ctn, which is aberrantly expressed or absent in human breast, colon and skin cancers. Kaiso is also a member of the POZ-zinc finger family of transcription factors implicated as oncoproteins or tumor suppressors, and currently it is the only known POZ protein with bi-modal DNA-binding and transcriptional repression activity.
From the laboratory of Juliet M. Daniel, PhD, McMaster Univeristy
Part of The Investigator's Annexe program.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Plasmid |
| Name: | Full-length Znf131 |
| Gene/insert name: | Znf131-FL |
| Antibiotic Resistance: | Amp |
| Fusion Tag(s): | GST |
| Grow in E. coli at 37 C: | Yes |
| Cloning Site 5': | BamHI |
| Cloning Site 3': | NotI |
| Vector Backbone and Size: | pGEX-5X-1 |
| Storage: | Up to 1 month at 4C. Long-term, -20C |
| Shipped: | Ambient temperature, spotted on filter paper |
pGEX-5X-1-Znf131 Plasmids
| Gene/Insert Name: | Znf131-FL | Znf131-ZF | Znf131-?ZF | Znf131-POZ | Znf131-?POZ |
| Description: | Full-length Znf131 | Znf131 Zinc finger Domain only | Znf131 with Zinc finger Domain deletion | Znf131 Pox virus and Zinc finger Domain (POZ) only | Znf131 with Pox virus and Zinc finger Domain deletion |
| Insert Size (bp): | 465 | ||||
| Species: | Human | Human | Human | Human | Human |
| Fusion Proteins/Tags: | GST | GST | GST | GST | GST |
| Vector Backbone and Size: | pGEX-5X-1 | pGEX-5X-1 | pGEX-5X-1 | pGEX-5X-1 | pGEX-5X-1 |
| Cloning Site 5': | BamHI | BamHI | BamHI | BamHI | BamHI |
| Cloning Site 3': | NotI | NotI | NotI | NotI | NotI |
| Antibiotic Resistance: | Amp | Amp | Amp | Amp | Amp |
| Standard E. coli @ 37C?: | Yes | Yes | Yes | Yes | Yes |
| Storage Temperature: | Up to 1 month at 4C. Long-term, -20C | ||||
| Shipped: | Room temperature, spotted on filter paper | ||||
- Donaldson NS, Nordgaard CL, Pierre CC, Kelly KF, Robinson S, Swystun L, Henriquez R, Graham M and Daniel JM. Kaiso regulates Znf131-mediated transcriptional activation. (2010) Exp. Cell Res. 316:1692-1705
If you publish research with this product, please let us know so we can cite your paper.
