Trans-Cyclooctene (TCO)-Amine is a simple carboxyl-reactive building block containing a TCO moiety and a terminal primary amine group.
TCO-Amine is a simple TCO-containing reagent possessing a terminal primary amines (–NH2) that reacts with carboxyl groups in the presence of activators (e.g. EDC, or DCC) or with activated esters (e.g. NHS esters) forming stable amide bonds. Short spacer arm adds minimal mass to modified molecules (262.8 daltons).
|Product Type:||Small Molecule|
|Name:||Trans-Cyclooctene (TCO)-Amine, HCl Salt|
|Purity:||>90% by reaction with NHS ester|
|Solubility:||DCM, Chloroform, DMSO, DMF|
|Storage:||Upon receipt store at -20C|
Applications: Protein-protein conjugation, protein-antibody conjugation, protein-small molecule conjugation, 18F radiolabeling, protein-oligonucleotide conjugation, surface modification
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