Trans-Cyclooctene (TCO)-PEG3-Maleimide is a mid-length, sulfhydryl-reactive labeling reagent containing a 3-unit polyethylene glycol spacer arm for increased water-solubility.
TCO-PEG3-Maleimide enables simple and efficient incorporation of TCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm provides a long and flexible connection that minimizes steric hindrance involved with ligation to complementary tetrazine-containing molecules.
|Product Type:||Small Molecule|
|Purity:||>90%, H NMR|
|Tested Applications:||Protein-protein conjugation, protein-antibody conjugation, protein-small molecule conjugation, 18F radiolabeling, protein-oligonucleotide conjugation, surface modification|
|Solubility:||DCM, Chloroform, DMSO, DMF|
|Storage:||Upon receipt store at -20C|
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