These mouse IgG2a,K monoclonal antibodies were generated against recombinant chicken Interleukin 7 (IL-7) and recognize chicken IL-7.
Interleukin 7 (IL-7), an important cytokine for B and T cell development, is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by a number of other cells (such as keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells), however, it is not produced by normal lymphocytes. Interleukin 7 (IL7) was originally discovered as a pre-B cell growth factor involved in immune and hematopoietic systems and its bioactivity assessed by stimulation of lymphoid progenitor proliferation, then renamed as IL7. Like in mammals, chIL7 induced proliferation of murine B cells and chicken primary lymphocytes isolated from spleen and bursa.
From the laboratory of United States Department of Agriculture/USDA
|Clone Name:||4F12, 1B7, 1H6, 3D3|
|Immunogen:||BL21-expressed chicken IL-7|
|Purification Method:||Protein A or A/G affinity purified|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB, ELISA|
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