Interferon kappa Antibodies

These mouse IgG1k & IgG2b,k monoclonal antibodies were generated against recombinant chicken Interferon kappa (IFN-k) and recognize chicken IFN-k.

Highlights:

  • Reacts with chicken IFN-k
  • May be useful for future research into innate immunity mediation by chicken IFN-k
  • Suitable for Western Blot and ELISA

Interferons (IFNs), a group of signaling proteins (glycoproteins), belong to the larger class of proteins known as cytokines. They play a major role in the early host response against pathogen invasion and their main function is to inhibit viral replication by interrupting the synthesis of viral RNAs and proteins. IFNs are classified as type I, type II, and type III IFNs, based on their functions and binding receptors. Type I IFNs, key mediators of innate and adaptive immune responses against pathogenic infections, are important in inflammation, immunoregulation, tumor cells recognition, and T-cell responses. They include several subclasses, such as, IFN-α, IFN-β, IFN-ω, IFN-ε, IFN-κ, and 11 IFN pseudogenes. Chicken IFN-κ seems to have anti-viral properties like those observed with type I IFNs. Due to this high anti-viral potential (important for the development of disease resistance), it may be very useful for further studying its capability to mediate innate immunity. (Also see Dev Comp Immunol. 2021 Nov;124:104204.)

From the laboratory of United States Department of Agriculture/USDA

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EUS087
Anti-Interferon kappa [11F11] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
EUS088
Anti-Interferon kappa [11F6] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
EUS090
Anti-Interferon kappa [5A3] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
EUS091
Anti-Interferon kappa [11E9] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
EUS089
Anti-Interferon kappa [3G3] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
Specifications

Product Type: Antibody
Antigen: Chicken IFN-k
Isotype: IgG1k; Clone 11F6: IgG2b,k
Clonality: Monoclonal
Clone Name: 3G3, 5A3, 11E9, 11F11, 11F6
Reactivity: Chicken
Immunogen: BL21-expressed chicken IFN-kappa
Species Immunized: Mouse
Purification Method: Protein A or A/G affinity purified
Buffer: PBS, 0.05% (w/v) Sodium Azide
Tested Applications: WB, ELISA
Storage: -20C
Shipped: Cold Packs

Provider
References
  1. Lee Y, Lu M, Lillehoj HS. Immunological studies on chicken interferon-kappa using an antigen-capture ELISA developed using new mouse monoclonal antibodies. Dev Comp Immunol. 2021 Nov;124:104204. doi: 10.1016/j.dci.2021.104204. Epub 2021 Jul 13. PMID: 34271063.

If you publish research with this product, please let us know so we can cite your paper.

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