This mouse IgG1 monoclonal antibody recognizes human, rat and hamster inosine-5'-monophosphate (IMP) dehydrogenase.
Recombinant versions available from our sister company, Absolute Antibody:
The enzyme inosine-5'-monophosphate (IMP) dehydrogenase is responsible for the rate-limiting step in guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis.
IMP dehydrogenase catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Because it is up-regulated in rapidly proliferating cells, human IMP dehydrogenase is actively targeted for immunosuppressive, anticancer, and antiviral chemotherapy.
From a laboratory at University of Chicago.
|Name:||Anti-Inosine-5'-monophosphate Dehydrogenase (1D6-3E)|
Recombinant versions: see product name
|Specificity:||This antibody recognizes hamster, rat, and human forms|
|Purification Method:||Protein G purified|
EZ2001: PBS with 0.05% (w/v) Sodium Azide
Recombinant versions: PBS with 0.02% Proclin 300
|Tested Applications:||Immunofluorescence, Western blot, ELISA|
|Storage:||Store at 4C|
If you publish research with this product, please let us know so we can cite your paper.