Anti-MHC Class I H2 Kb [AF6-88.5.5.3] Antibody

This mouse IgG2a monoclonal antibody was generated against H-2Kb, and recognizes mouse H2Kb MHC Class I.

Recombinant versions available from our sister company, Absolute Antibody:

MHC Class I H-2 Kb is involved in the presentation of foreign antigens to the immune system. The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant Beta2-microglobulin. These antigens are expressed on most nucleated cells, but expression varies on different cell types. MHC Class I molecules present intracellular processed peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. This results in a cytoxic effector response against the presenting cell. Additionally, MHC Class I antigens are expressed on thymic epithelial cells, which is an important regulation step during the positive and negative selection of CD8+ T cells during T cell ontogeny.

From a laboratory at University of Chicago.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EZ1002
Anti-MHC Class I H2 Kb [AF6-88.5.5.3] Antibody
100ug 4-6 weeks
Regular Price:$321.00
On Sale:
Kf-Ab02570-10.0
Recombinant MHC Class I H2 Kb [AF6-88.5.5.3], Human, IgG1k
200ug 4-6 weeks
Regular Price:$430.00
On Sale:
Kf-Ab02570-10.3
Recombinant MHC Class I H2 Kb [AF6-88.5.5.3], Human, IgG1k, Fc Silent
200ug, Fc Silent 4-6 weeks
Regular Price:$430.00
On Sale:
Kf-Ab02570-2.0
Recombinant MHC Class I H2 Kb [AF6-88.5.5.3], Mouse, IgG2a
200ug 4-6 weeks
Regular Price:$430.00
On Sale:
Kf-Ab02570-2.3
Recombinant MHC Class I H2 Kb [AF6-88.5.5.3], Mouse, IgG2a, Fc Silent
200ug, Fc Silent 4-6 weeks
Regular Price:$430.00
On Sale:
Kf-Ab02570-23.0
Recombinant MHC Class I H2 Kb [AF6-88.5.5.3], Rabbit, IgGk
200ug 4-6 weeks
Regular Price:$430.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-Mouse H-2Kb MHC Class I (AF6-88.5.5.3)
Accession ID: O19468
Host: Mouse
Isotype: EZ1002: IgG2a
Recombinant versions: see product name
Clonality: Monoclonal
Clone Name: AF6-88.5.5.3
Specificity: This antibody recognizes mouse H-2Kb MHC Class I
Immunogen: H-2Kb
Format: Liquid
Purification Method: Protein G purified
Buffer: EZ1002: PBS with 0.05% (w/v) Sodium Azide
Recombinant versions: PBS with 0.02% Proclin 300
Tested Applications: Immunofluorescence, flow cytometry, immunoprecipitation, immunohistology
Concentration: 1mg/mL
Amount: 100uL
Storage: Store at 4C
Shipped: Cold packs

Provider
From a laboratory at University of Chicago.
References
  1. Wall, K.A., et al. Inhibition of Proliferation of Mis- and la-Reactive Cloned T Cells by a Monoclonal Antibody Against a Determinant Shared by I-A and LE. The Journal of Immunology. 131(3): 1056 - 1064. 1983.

If you publish research with this product, please let us know so we can cite your paper.

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