Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8] Antibody

This IgG2b mouse antibody was generated against amino acids 37-53 of rat GABA-A receptor gamma2 subunit GABRG2 and is specific for the N-terminal extracellular domain, allowing for the detection of surface expressed receptors for live imaging.

Highlights:

  • Reacts with GABA-A Receptor Gamma 2 Subunit
  • Suitable for Western Blot, Immunoblot, Immunohistochemistry and Immunofluorescence applications

Recombinant versions available from our sister company, Absolute Antibody:

GABA-A receptors are ligand-gated neurotransmitter receptors that function to mediate the fast synaptic inhibition within the brain. They are pentamers, composed from a variety of classes of subunits with gamma being just one class. Each subunit is composed of an extracellular N-terminal domain, four membrane spanning units, and a small extracellular C-terminal segment. Several mutations in the GABA(A) receptor subunit gamma-2 expression have been linked to epileptic syndromes that result in fibrile seizures.

From the laboratory of Jaideep Kapur, MD, PhD, University of Virginia.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EG1401
Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8] Antibody
50ug Limited stock
Regular Price:$299.00
On Sale:
Kf-Ab01119-23.0
Recombinant Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8], Rabbit, IgGk
200ug In stock
Regular Price:$370.00
On Sale:
Kf-Ab01119-3.0
Recombinant Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8], Mouse, IgG2bk
200ug In stock
Regular Price:$370.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8]
Accession ID: NP_899156
Antigen: GABA-A Receptor Gamma 2 Subunit
Isotype: EG1401: IgG2b
Recombinant versions: see product name
Clonality: Monoclonal
Clone Name: 10F10-C1-B8
Reactivity: Reactive against the N-terminal extracellular domain (amino acids 37-53) of the gamma2 subunit of the GABA-A protein in rats
Immunogen: Generated against the gamma2 subunit of the GABA-A protein from rats
Species Immunized: Mouse
Epitope: N-terminal extracellular domain (amino acids 37-53)
Purification Method: Protein G
Buffer: EG1401: PBS, 0.05% (w/v) Sodium Azide
Recombinant versions: PBS with 0.02% Proclin 300
Tested Applications: WB, IF, IHC, IP
Concentration: 1mg/mL
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Jaideep Kapur, MD, PhD, University of Virginia.
Comments

For western blot, 1:2,000 dilution recommended.

For IHC, 1:250 dilution recommeneded.

References
  1. Joshi S, Sun C, Kapur J. A mouse monoclonal antibody against the gamma2 subunit of GABA-A receptors. Hybridoma. 30(6): 537-42 (2011).

If you publish research with this product, please let us know so we can cite your paper.

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