Anti-Flavivirus E Protein [D1-4G2-4-15] Antibody

This mouse IgG2a monoclonal antibody was generated against flavivirus envelope proteins and recognizes the domain II of protein E (fusion loop) of flavivirus.

Highlights:

  • Recognizes Dengue virus, West Nile Virus, Japanese Encephalitis and Zika virus
  • Suitable for Immunofluorescence applications

Recombinant versions available from our sister company, Absolute Antibody:

The flavivirus inlcudes West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis. Flaviviruses have a (+) sense RNA genome and replicate in the cytoplasm of the host cells. The genome mimics the cellular mRNA molecule in all aspects except for the absence of the poly-adenylated (poly-A) tail. This feature allows the virus to exploit cellular apparatus to synthesise both structural and non-structural proteins, during replication.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
FCG001
Anti-Flavivirus E Protein [D1-4G2-4-15] Antibody
100ug In stock
Regular Price:$360.00
On Sale:
Kf-Ab00230-10.0
Recombinant Anti-Flavivirus E Protein [D1-4G2-4-15], Human, IgG1k
200ug In stock
Regular Price:$390.00
On Sale:
Kf-Ab00230-15.0
Recombinant Anti-Flavivirus E Protein [D1-4G2-4-15], Human, IgMk
50ug In stock
Regular Price:$525.00
On Sale:
Kf-Ab00230-2.0
Recombinant Anti-Flavivirus E Protein [D1-4G2-4-15], Mouse, IgG2ak
200ug In stock
Regular Price:$390.00
On Sale:
Kf-Ab00230-21.0
Recombinant Anti-Flavivirus E Protein [D1-4G2-4-15], Mouse, IgMk
50ug In stock
Regular Price:$525.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-Flavivirus E Protein [D1-4G2-4-15] Antibody
Antigen: Flavivirus Envelope (E) Protein
Isotype: FCG001: IgG2a kappa
Recombinant versions: see product name
Clonality: Monoclonal
Clone Name: D1-4G2-4-15
Reactivity: Virus
Specificity: Virus
Immunogen: Flavivirus envelope proteins
Species Immunized: Mouse
Purification Method: Protein G
Buffer: FCG001:PBS, pH 7.2
Recombinant versions: PBS with 0.02% Proclin 300
Tested Applications: IF
Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
Shipped: Cold packs

Data

Detection of ZIKV via immunofluorescence

Sample confocal images of forebrain-specific hNPCs 56 hr after infection with ZIKV supernatant, immunostained for ZIKV envelop protein (ZIKVE; green) and DAPI (gray). Cells were differentiated from the C1-2 hiPSC line. Scale bars, 20 ?m.

Adapted from: Tang H, et al. Cell Stem Cell. 2016 May 5;18(5):587-90.

References
  1. Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell Stem Cell. 2016 May 5;18(5):587-90.

If you publish research with this product, please let us know so we can cite your paper.

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