PC3-ML-Luciferase Prostate Cancer Cell Line

PC3-ML Luciferase cell line are luciferase expressing prostate cancer cells derived from a metastatic bone.

Highlights:

  • Luciferase stable PC3 cells can be a very useful cell line for non-invasive visualization in in vitro experiments

Luciferase is commonly used as a reporter to assess the transcriptional activity of a genetic construct with luciferase gene under the promoter of interest. Luciferase stable PC3 Cells is a luciferase expressing cell line derived from PC3 cells. Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system. The androgen receptor (AR) helps prostate cancer cells to survive and is a target for many anti cancer research studies by looking at inhibition.

From the laboratory of Mauricio J. Reginato, PhD, Drexel University.

Catalog Number Product Size AVAILABILITY Price Qty
EDX002
PC3-ML-Luciferase Prostate Cancer Cell Line
1 vial 3-5 weeks
Price: $499.00
Specifications
Product Type: Cell Line
Organism: Human
Source: Prostate
Morphology: Epithelial
Biosafety Level: BSL 1
Subculturing: A subcultivation ratio of 1:3 to 1:6 is recommended, Medium Renewal: 2 to 3 times per week
Growth Conditions: The base medium for this cell line is ATCC-formulated F-12K Medium, Catalog No. 30-2004. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10% and penn/strep.
Cryopreservation: Complete growth medium supplemented with 5% (v/v) DMSO
Comments: Expressing luciferase gene for in vivo bioluminescence analysis
Storage: LN2
Shipped: Dry Ice
Provider
From the laboratory of Mauricio J. Reginato, PhD, Drexel University.
References
  1. Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. J Biol Chem. 2012 Mar 30;287(14):11070-81.
  2. Wang M, Stearns ME. Isolation and characterization of PC-3 human prostatic tumor sublines which preferentially metastasize to select organs in S.C.I.D. mice. Differentiation. 1991 Nov;48(2):115-25. PubMed PMID: 1773917.

If you publish research with this product, please let us know so we can cite your paper.

 
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