Insulin-like growth factor-binding proteins (IGFBPs) are involved in mediating the effects of insulin-like growth factor (IGF) actions in a wide variety of cell types. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. IGFBP-2 is the second most abundant IGFBP in the circulation and is present in various other biological fluids and tissues of many vertebrate species. Serum IGFBP-2 levels are elevated in conditions such as shock, fasting, hypoxemia or after traumata, suggesting complex regulation of IGFBP-2 expression.
Sample Requirements: Serum
Minimum Sample Volume: 15uL
From the laboratory of Clifford J. Rosen, PhD, Maine Medical Center Research Institute.
Part of The Investigator's Annexe program.