Insulin-like growth factor-binding proteins (IGFBPs) are involved in mediating the effects of insulin-like growth factor (IGF) actions in a wide variety of cell types. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. IGFBP-2 is the second most abundant IGFBP in the circulation and is present in various other biological fluids and tissues of many vertebrate species. Serum IGFBP-2 levels are elevated in conditions such as shock, fasting, hypoxemia or after traumata, suggesting complex regulation of IGFBP-2 expression.
Sample Requirements: Serum or Plasma
Minimum Sample Volume: 50uL
From the laboratory of Clifford J. Rosen, PhD, Maine Medical Center Research Institute.
Part of The Investigator's Annexe program.
All samples will be tested in duplicate and compared to standards and contorls.
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