CTHRC1 (collagen triple helix repeat containing 1) is a 243 amino acid secreted protein that localizes to the extracellular matrix and contains one collagen-like domain. Expressed as two alternatively spliced isoforms, the first of which is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, CTHRC1 is thought to function as a negative regulator of collagen matrix deposition and may also play a role in the stabilization of ligand-receptor interactions in the Wnt pathway. CTHRC1 is widely present in a variety of cancers, including melanoma and breast carcinoma, and may participate in cancer cell migration and cancer tissue invasion and metastasis.
Highlights
Available Cthrc1 ELISA Kit & Antibodies
Anti-CTHRC1 [Vli13E09] Antibody
Anti-CTHRC1, C-terminal [Vli55] Antibody (supernatant)
Anti-CTHRC1, N-terminal [Vli19C07] Antibody