Anti-CD44 [IM7.8.1] Hybridoma
![Anti-CD44 [IM7.8.1] Hybridoma](https://www.kerafast.com/MediaStorage/Product/Images/Large/3571_2001202001281435700.jpg "Anti-CD44 [IM7.8.1] Hybridoma")
This hybridoma line produces a rat anti-mouse CD44 monoclonal antibody (clone IM7.8.1).
CD44 is a glycoprotein that is ubiquitously expressed in most cells throughout the body and involved in cell adhesion, migration, differentiation, and survival. It has been found to be up regulated in various types of cancer stem cells, such as those of the prostate, pancreas, brain, and blood. CD44 overexpression in cancer stem cells leads to high resistance to chemotherapy and radiation treatment and an increase in metastasis.
This hybridoma line produces a rat anti-mouse CD44 monoclonal antibody (clone IM7.8.1).
CD44 is a glycoprotein that is ubiquitously expressed in most cells throughout the body and involved in cell adhesion, migration, differentiation, and survival. It has been found to be up regulated in various types of cancer stem cells, such as those of the prostate, pancreas, brain, and blood. CD44 overexpression in cancer stem cells leads to high resistance to chemotherapy and radiation treatment and an increase in metastasis.
Specifications
| Product Type: | Antibody |
| Name: | Anti-CD44 [IM7.8.1] Hybridoma |
| Cell Type: | Hybridoma Cell Line |
| Antigen: | CD44 |
| Isotype: | IgG2b |
| Clonality: | Monoclonal |
| Clone Name: | IM7.8.1 |
| Reactivity: | Mouse |
| Specificity: | CD44 |
| Growth Conditions: | Dulbeccos Modified Eagles medium (DMEM) + 10% fetal bovine serum (FBS) + non-essential amino acid + sodium pyruvate + 50uM beta-mercaptoethanol |
| Immunogen: | Myeloid cell line M1 |
| Cryopreservation: | Resuspend cells in DMEM, 20% FBS, and 10% DMSO. Store in liquid nitrogen. |
| Species Immunized: | Rat |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
References
- lmmunogenetics (1982) 15:299-312
- J lmmunol (1994) 153:3440-3449
- Adv lmmunol (1993) 54:271-335
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