Anti-Caspase 7 [20F3] Antibody
This IgG2a rat monoclonal antibody was generated against the bacterial fusion protein (large subunit) and recognizes human caspase 7.
Caspase 7, an enzyme encoded by the CASP7 gene in humans, is a member of the cysteine-aspartic acid protease family. Sequential activation of the caspases is critical for cell apoptosis; caspase 7 has been shown to be an executioner protein in this cascade.
From a laboratory at Harvard University.
Part of The Investigator's Annexe program.
This IgG2a rat monoclonal antibody was generated against the bacterial fusion protein (large subunit) and recognizes human caspase 7.
Caspase 7, an enzyme encoded by the CASP7 gene in humans, is a member of the cysteine-aspartic acid protease family. Sequential activation of the caspases is critical for cell apoptosis; caspase 7 has been shown to be an executioner protein in this cascade.
From a laboratory at Harvard University.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Name: | Anti-Caspase 7 (20F3) |
| Accession ID: | P55210 |
| Host: | Rat |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 20F3 |
| Specificity: | Caspase 7 (human) |
| Immunogen: | Bacterial fusion protein(Large subunit) |
| Format: | Liquid |
| Purification Method: | Protein G affinity purified |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, ELISA |
| Concentration: | 1mg/mL |
| Amount: | 100uL |
| Storage: | Store at 4C |
| Shipped: | Cold packs |
Provider
From a laboratory at Harvard University.
References
- Michael Boyce et al. A selective Inhibitor of eIF2a Dephosphorylation Protects Cells from ER Stress. Science Vol. 307, 11 February, 2005
- SJ Kang. Et al. Distinct downstream pathways of Caspase-11 in regulating apoptosis and cytokine maturation during septic shock response. Cell Death and Differentiation(2002) 9, 1115-1125
- Honglin Li et al. Cleavage of Bid by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis. Cell, Vol. 94, 491-501, August 21, 1998
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