Anti-Bone Sialoprotein (BSP), Y278-D295 [LF-84] Antibody
![Anti-Bone Sialoprotein (BSP), Y278-D295 [LF-84] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1534_2001202001265115330.jpg "Anti-Bone Sialoprotein (BSP), Y278-D295 [LF-84] Antibody")
This rabbit IgG polyclonal antibody was generated against peptide and recognizes human and most mammals bone sialoprotein (BSP).
Highlights:
- Recognizes human and most mammals BSP- Epitope YESENGEPRGDNYRAYED
- Suitable for Immunohistochemistry and Western Blot applications
Bone sialoprotein (BSP) is a component of tissues such as bone, dentin, cementum and calcified cartilage. BSP is a phosphorylated glycoprotein and has been found in cells such as osteoblasts and osteocytes. Bone sialoprotein could be a potential serum marker for monitoring bone remodelling.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This rabbit IgG polyclonal antibody was generated against peptide and recognizes human and most mammals bone sialoprotein (BSP).
Highlights:
- Recognizes human and most mammals BSP- Epitope YESENGEPRGDNYRAYED
- Suitable for Immunohistochemistry and Western Blot applications
Bone sialoprotein (BSP) is a component of tissues such as bone, dentin, cementum and calcified cartilage. BSP is a phosphorylated glycoprotein and has been found in cells such as osteoblasts and osteocytes. Bone sialoprotein could be a potential serum marker for monitoring bone remodelling.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
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| Product Type: | Antibody |
| Antigen: | Bone Sialoprotein (BSP), human |
| Accession ID: | P21815 |
| Molecular Weight: | 35148 Da |
| Clonality: | Polyclonal |
| Clone Name: | LF-84 |
| Reactivity: | Human and most mammals |
| Immunogen: | Peptide |
| Species Immunized: | Rabbit |
| Epitope: | YESENGEPRGDNYRAYED |
| Buffer: | Whole serum |
| Tested Applications: | WB 1:2000, IHC 1:200 |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5. PubMed PMID: 8553864.
- Jeong-Seok Nam, Adam M. Suchar, Mi-Jin Kang, Christina H. Stuelten, Binwu Tang, Aleksandra M. Michalowska, Larry W. Fisher, Neal S. Fedarko, Alka Jain, Jan Pinkas, Scott Lonning, Lalage M. Wakefield. Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of TGF-? in a mouse model of breast cancer. Cancer Res. 2006 Jun 15; 66(12): 63276335.
- Miwa HE, Gerken TA, Jamison O, Tabak LA. Isoform-specific O-glycosylation of osteopontin and bone sialoprotein by polypeptide N-acetylgalactosaminyltransferase-1. J Biol Chem. 2010 Jan 8;285(2):1208-19.
- Karadag A, Ogbureke KU, Fedarko NS, Fisher LW. Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion.J Natl Cancer Inst. 2004 Jun 16;96(12):956-65.
- Calloni GW, Le Douarin NM, Dupin E. High frequency of cephalic neural crest cells shows coexistence of neurogenic, melanogenic, and osteogenic differentiation capacities. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8947-52
- Ogbureke KU, Abdelsayed RA, Kushner H, Li L, Fisher LW. Two members of the SIBLING family of proteins, DSPP and BSP, may predict the transition of oral epithelial dysplasia to oral squamous cell carcinoma. Cancer. 2010 Apr 1;116(7):1709-17.
- Ogbureke KU, Fisher LW. Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs). Kidney Int. 2005 Jul;68(1):155-66.
- Knabe C, Kraska B, Koch C, Gross U, Zreiqat H, Stiller M. A method for immunohistochemical detection of osteogenic markers in undecalcified bone sections. Biotech Histochem. 2006 Jan-Feb;81(1):31-9.
- Yamauchi N, Nagaoka H, Yamauchi S, Teixeira FB, Miguez P, Yamauchi M. Immunohistological characterization of newly formed tissues after regenerative procedure in immature dog teeth. J Endod. 2011 Dec;37(12):1636-41
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