Anti-Versican [LF-99] Antibody
![Anti-Versican [LF-99] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1509_2001202001265015080.jpg "Anti-Versican [LF-99] Antibody")
This rabbit IgG polyclonal antibody was generated against peptide and recognizes human and primate versican.
Highlights:
- Recognizes human and primate veriscan - Epitope amino acid sequence LHKVKVGKSPPVRC
- Suitable for Immunohistochemistry and Western Blot applications
Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissue. Versican is a large chondroitin sulfate proteoglycan with a large molecular mass (over 1000 kDa ). Versican is often considered an anti-adhesion molecule due it's large size. Expression of versican is observed in various adult tissues such as blood vessels, skin, and developing heart.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This rabbit IgG polyclonal antibody was generated against peptide and recognizes human and primate versican.
Highlights:
- Recognizes human and primate veriscan - Epitope amino acid sequence LHKVKVGKSPPVRC
- Suitable for Immunohistochemistry and Western Blot applications
Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissue. Versican is a large chondroitin sulfate proteoglycan with a large molecular mass (over 1000 kDa ). Versican is often considered an anti-adhesion molecule due it's large size. Expression of versican is observed in various adult tissues such as blood vessels, skin, and developing heart.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This product is for sale to Nonprofit customers only. For profit customers, please Contact Us for more information.
| Product Type: | Antibody |
| Antigen: | Versican, human |
| Accession ID: | P13611 , NP_004376.2 |
| Molecular Weight: | 372820 Da |
| Clonality: | Polyclonal |
| Clone Name: | LF-99 |
| Reactivity: | Human and other primates |
| Immunogen: | Peptide |
| Species Immunized: | Rabbit |
| Epitope: | LHKVKVGKSPPVRC |
| Buffer: | Whole serum |
| Tested Applications: | WB 1:1000, IHC 1:200 |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5. PubMed PMID: 8553864.
- Ruggeri A, Orsini G, Mazzoni A, Nato F, Papa V, Piccirilli M, Putignano A, Mazzotti G, De Stefano Dorigo E, Breschi L. Immunohistochemical and biochemical assay of versican in human sound predentine/dentine matrix. Eur J Histochem. 2009 Sep 23;53(3):125-33. PubMed PMID: 19864206.
- Hinek A, Braun KR, Liu K, Wang Y, Wight TN. Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients. Am J Pathol. 2004 Jan;164(1):119-31. PubMed PMID: 14695326; PubMed Central PMCID: PMC1602235.
- Merrilees MJ, Ching PS, Beaumont B, Hinek A, Wight TN, Black PN. Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease. Respir Res. 2008 May 18;9:41.
- Röck K, Meusch M, Fuchs N, Tigges J, Zipper P, Fritsche E, Krutmann J, Homey B, Reifenberger J, Fischer JW. Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes. J Biol Chem. 2012 Jun 8;287(24):20056-69.
- Gao G, Plaas A, Thompson VP, Jin S, Zuo F, Sandy JD. ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J Biol Chem. 2004 Mar 12;279(11):10042-51. Epub 2003 Dec 29. PubMed PMID: 14701864.
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