Anti-EEA1 [1G11] Antibody
![Anti-EEA1 [1G11] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1096_2001202001263410950.jpg "Anti-EEA1 [1G11] Antibody")
This mouse IgG1 monoclonal antibody [1G11] was generated against recombinant protein and recognizes human and rabbit early endosome antigen 1 (EEA1).
Highlights:
- Reacts with human and rabbit EEA1
- Suitable for Western Blot and Indirect Immunofluorescence applications
Early endosome antigen 1 (EEA1) has been show to bind phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Antibodies against EEA1 has been found in patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
Part of The Investigator's Annexe program.
This mouse IgG1 monoclonal antibody [1G11] was generated against recombinant protein and recognizes human and rabbit early endosome antigen 1 (EEA1).
Highlights:
- Reacts with human and rabbit EEA1
- Suitable for Western Blot and Indirect Immunofluorescence applications
Early endosome antigen 1 (EEA1) has been show to bind phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Antibodies against EEA1 has been found in patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
Part of The Investigator's Annexe program.
Specifications
| Product Type: | Antibody |
| Alternative Name(s): | MST105; MSTP105; ZFYVE2; early endosome antigen 1; early endosome antigen 1, 162kD; early endosome-associated protein; Endosome-associated protein p162; MSTP105; ZFYVE2; ZFYVE2MST105; Zinc finger FYVE domain-containing protein 2 |
| Antigen: | EEA1 (Early endosome antigen) |
| Accession ID: | Q15075, NP_003557 |
| Molecular Weight: | 162 kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | 1G11 |
| Reactivity: | Human and rabbit |
| Immunogen: | Recombinant protein |
| Species Immunized: | Mouse |
| Buffer: | Cell media supernatant |
| Tested Applications: | WB (1:100-1:500), IF |
| Storage: | -80C |
| Shipped: | Cold Packs |
Provider
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
References
- Selak S, Mahler M, Miyachi K, Fritzler ML, Fritzler MJ. Identification of the B-cell epitopes of the early endosome antigen 1 (EEA1). Clin Immunol 2003; 109:154-64.
- Selak S, Braun JE, Fritzler MJ. Characterization of early endosome antigen 1 in neural tissues. Biochem Biophys Res Commun 2004; 323:1334-42.
- Selak S, Fritzler MJ. Altered neurological function in mice immunized with early endosome antigen 1. BMC Neurosci 2004; 5:2.
- Selak S, Paternain AV, Fritzler MJ, Lerma J. Human autoantibodies against early endosome antigen-1 enhance excitatory synaptic transmission. Neuroscience 2006; 143:953-64.
If you publish research with this product, please let us know so we can cite your paper.
