Jihong Bai, PhD, Fred Hutchinson Cancer Research Center

Jihong Bai, PhD
Jihong Bai, PhD

Dr. Bai's laboratory research goal is to understand how synapses develop into functional circuits. Synaptic connections undergo constant fine-tuning to support information delivery and storage in the brain. Regulation of these connections can occur through altering the strength of existing synapses or through synapse assembly and disassembly. They utilize a combination of genetic, biochemical, imaging, and electrophysiological techniques to ask biological questions at the levels of individual synapses and functional circuits.

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References

  1. Poudel KR, Roh-Johnson M, Su A, Ho T, Mathsyaraja H, Anderson S, Grady WM, Moens CB, Conacci-Sorrell M, Eisenman RN, Bai J. Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Dev Cell. 2018 Jun 18;45(6):738-752.e6. doi: 10.1016/j.devcel.2018.05.021. PubMed PMID: 29920278.