Brian J. Geiss, PhD, Colorado State University

Brian J. Geiss, PhD
Brian J. Geiss, PhD

A major focus of the Geiss laboratory is studying the biochemistry of flavivirus NS5 RNA capping enzyme. The capping enzyme is a multifunctional protein that forms the mature viral RNA cap that directs viral polyprotein translation and protects the viral genome from degradation.

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References

  1. Terry JS, Anderson LB, Scherman MS, McAlister CE, Perera R, Schountz T, Geiss BJ. Development of SARS-CoV-2 Nucleocapsid Specific Monoclonal Antibodies. bioRxiv [Preprint]. 2020 Sep 3:2020.09.03.280370. doi: 10.1101/2020.09.03.280370. PMID: 32908982; PMCID: PMC7480041.
  2. Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD. Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone. J Virol. 2016 Dec 16;91(1). pii: e01765-16. Print 2017 Jan 1. Erratum in: J Virol. 2017 Mar 29;91(8):. PubMed PMID: 27795432
  3. Geiss BJ, Shimonkevitz LH, Sackal CI, Olson KE. Recombination-ready Sindbis replicon expression vectors for transgene expression. Virol J. 2007 Oct 26;4:112.PubMed PMID: 17963504; PubMed Central PMCID: PMC2164957.
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