Jeffrey D. Erickson, PhD, Louisiana State University Health Sciences Center New Orleans

Jeffrey D. Erickson, PhD
Jeffrey D. Erickson, PhD

The Erickson laboratory focuses on two areas of research; 1) Vesicular glutamate transporters in the regulation of glutamate release, specifically studying synaptic vesicles that express VGLUT1 and VGLUT2 and 2) The role of neuronal glutamine transporters (SNAT family) in glutamatergic neurotransmission.

Products

References

  1. Varoqui H, Zhu H, Yao D, Ming H, Erickson JD. Cloning and functional identification of a neuronal glutamine transporter. J Biol Chem. 2000 Feb 11;275(6):4049-54. PubMed PMID: 10660562.
  2. Mackenzie B, Schäfer MK, Erickson JD, Hediger MA, Weihe E, Varoqui H. Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. J Biol Chem. 2003 Jun 27;278(26):23720-30. Epub 2003 Apr 8. PubMed PMID: 12684517.
  3. Yao D, Mackenzie B, Ming H, Varoqui H, Zhu H, Hediger MA, Erickson JD. A novel system A isoform mediating Na+/neutral amino acid cotransport. J Biol Chem. 2000 Jul 28;275(30):22790-7. PubMed PMID: 10811809.
  4. Grewal S, Defamie N, Zhang X, De Gois S, Shawki A, Mackenzie B, Chen C, Varoqui H, Erickson JD. SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission. J/Biol Chem. 2009 Apr 24;284(17):11224-36
  5. Varoqui H, Erickson JD. Selective up-regulation of system a transporter mRNA in diabetic liver. Biochem Biophys Res Commun. 2002 Jan 25;290(3):903-8. PubMed PMID: 11798158.
  6. He H, Mahnke AH, Doyle S, Fan N, Wang CC, Hall BJ, Tang YP, Inglis FM, Chen C, Erickson JD. Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning. J Neurosci. 2012 Nov 7;32(45):15886-901.
  7. Doyle S, Pyndiah S, De Gois S, Erickson JD. Excitation-transcription coupling via calcium/calmodulin-dependent protein kinase/ERK1/2 signaling mediates the coordinate induction of VGLUT2 and Narp triggered by a prolonged increase in glutamatergic synaptic activity. J Biol Chem. 2010 May 7;285(19):14366-76.
  8. Wilson NR, Kang J, Hueske EV, Leung T, Varoqui H, Murnick JG, Erickson JD, Liu G. Presynaptic regulation of quantal size by the vesicular glutamate transporter VGLUT1. J Neurosci. 2005 Jun 29;25(26):6221-34. Erratum in: J Neurosci. 2005 Jul 27;25(30):7100. PubMed PMID: 15987952.
  9. De Gois S, Schäfer MK, Defamie N, Chen C, Ricci A, Weihe E, Varoqui H, Erickson JD. Homeostatic scaling of vesicular glutamate and GABA transporter expression in rat neocortical circuits. J Neurosci. 2005 Aug 3;25(31):7121-33. PubMed PMID: 16079394.