These mouse monoclonal antibodies were raised against recombinant chicken interleukin 6 (IL-6)-MBP and recognize chicken IL-6.
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine (cytokine produced from muscle). IL-6 is an important mediator of fever and of the acute phase response and osteoblasts secrete IL-6 to stimulate osteoclast formation. IL-6 stimulates the inflammatory and auto-immune processes in many diseases including diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, Behcet's disease, rheumatoid arthritis, and intracerebral hemorrhage. Many companies target anti-IL6 reagents as therapies for these diseases.
From a laboratory at United States Department of Agriculture/USDA.
Clone 1.15.4: IgG2a
Clone 1.26.4: IgG2b
Other clones unknown
|Purification Method:||Protein G|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB, ELISA|
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