10-Gingerol

10-Gingerol is isolated from the rhizomes or roots of the plant Zingiber officinale (ginger).

10-Gingerol is one of several active compounds isolated from the ginger root. 10-Gingerol is believed to inhibit the anti-serotonin 3 receptor function leading to anti-emetic properties. Additionally, it has been shown to affect gastric motility and potentially have an antispasmodic effect on the gastrointestinal system.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
FAP035
10-Gingerol, 5mg
5mg 1-2 weeks
Regular Price:$164.50
On Sale:
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FAP036
10-Gingerol, 25mg
25mg 1-2 weeks
Regular Price:$658.00
On Sale:
Specifications

Product Type: Small Molecule
Chemical Formula: C21H34O4
CAS number: 23513-15-7
Molecular Weight: 350.49
Format: Light yellow powder
Purity: >98 % determined by HPLC
Solubility: Soluble in methanol and ethanol
Stability: Stable over extended period at -20C.
Storage: -20C, avoid exposure to oxygen and direct sunlight
Shipped: Cold Pack

Data

10-Gingerol HPLC Chromatogram.


Purification Notes: Purification is conducted using near-critical and super-critical fluids during extraction from the ginger root.

References
  1. Ali B, Blunden G, Tanira M and Nemmar A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food and Chemical Toxicology. 46(2): 409-420.
  2. Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Klein S, Riggins C and Rister R. (1998). The Complete German Commission E monographs. Therapeutic Guide to Herbal Medicines, Austin TX, American Botanical Council.
  3. Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, Leeprakobboon K and Leelasettagool C. (2006). The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am. J. Obstet. Gynecol. 194, 95–99.
  4. Chen C, Kuo M, Wu C and Ho C. (1986). Pungent Compounds of Ginger (Zingiber officinale Roscoe) Extracted by Liquid Carbon Dioxide. Journal of Agriculture and Food Chemistry 34(3): 477-480.
  5. Hashimoto K, Satoh K, Murata P, Makino B, Sakakibara I, Kase Y, Ishige A, Higuchi M and Sasaki H. (2002). Component of Zingiber officinale that improves the enhancement of small intestinal transport. Planta Medica. 68:936-9.
  6. Huang Q, Iwamoto M, Aoki S, Tanaka N, Tajima K, Yamahara J, Takaishi Y, Yoshida M, Tomimatsu T and Tamai Y. (1991). Anti-5-hydroxytryptamine 3 effect of galanolactone, diterpenoid isolated from ginger. Chem. Pharm. Bull. (Tokyo) 39, 397–399.
  7. Suekawa M, Ishige A, Yuasa K, Sudo K, Aburada M and Hosoya E. (1984). Pharmacological studies on ginger: I. Pharmacological action of pungent constituents, (6)-gingerol and (6)-shogaol. J Pharmacobiodyn. 7:836-48.
  8. Yamahara J, Rong H, Iwamoto M, Kobayashi G, Matsuda H and Fujimura H. (1989). Active components of ginger exhibiting anti-serotonergic action. Phytother. Res. 3, 70–71.

If you publish research with this product, please let us know so we can cite your paper.

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