Bryostatin 2 is one of a series of cyclic macrolides isolated from the marine bryozoan Bugula neritina (Order Cheilostomata), and a potent modulator of Protein Kinase C (PKC).
Bryostatin 2 is a macrocyclic lactone with anti-tumor properties and a potent activator of Protein Kinase C (PKC), which inhibits the growth of A549 cells. Bryostatin 2 has been documented to compete with phorbol ester binding to PKC at a Ki= 3.4 nM, a Ki
|Product Type:||Small Molecule|
|Format:||White crystalline solid|
|Purity:||>95 % determined by HPLC|
|Solubility:||Soluble in methanol and ethanol|
|Stability:||Stable as a solid over extended period at -20C.|
|Storage:||-20C, avoid exposure to oxygen and direct sunlight|
Bryostatin 2 HPLC Chromatogram.
Purification Notes: Purified using near-critical and supercritical fluids as an alternate to conventional organic solvents during a sequence of phase extraction and chromatographic purification steps.
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