This S195A inactived human alpha thrombin protein was expressed recombinantly in E. Coli and purified to >95% (by SDS-PAGE).
Thrombin is a serine protease that possesses trypsin-like behavior in that it prefers to cleave its substrates after arginine and lysine residues. It elicits functional responses critical to blood homeostasis by interacting with diverse physiological substrates.
From the laboratory of Enrico Di Cera, MD, St. Louis University.
Part of The Investigator's Annexe program.
|Name:||Human Alpha Thrombin (S195A)|
|Accession ID:||P00734, NM_000506|
|Molecular Weight:||33.6 kDa|
|Amino Acid Sequence:||TFGSGEADCG LRPLFEKKSL EDKTERELLE SYIDGRIVEG SDAEIGMSPW QVMLFRKSPQ ELLCGASLIS DRWVLTAAHC LLYPPWDKNF TENDLLVRIG KHSRTRYERN IEKISMLEKI YIHPRYNWRE NLDRDIALMK LKKPVAFSDY IHPVCLPDRE TAASLLQAGY KGRVTGWGNL KETWTANVGK GQPSVLQVVN LPIVERPVCK DSTRIRITDN MFCAGYKPDE GKRGDACEGD (S>A)GGPFVMKSP FNNRWYQMGI VSWGEGCDRD GKYGFYTHVF RLKKWIQKVI DQFGE|
|Purity:||>95% by SDS-PAGE|
|Buffer:||300mM NaCl, 20mM Tris pH 7.4|
|Comments:||The referenced sequences are processed to produce the alpha form of the enzyme.|
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