FAK Antibodies
![Anti-FAK [3C4] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-FAK [3C4] Antibody")
These mouse IgG1 antibodies were generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing activated forms of pp60srC (pp6027F or pp602A/527F) and recognize chicken focal adhesion kinase (FAK).
Highlights:
- Reacts with chicken FAK
- May be useful for signal transduction pathways reserach, as well as oncogenic studies
- Suitable for Western Blot and Immunoprecipitation applications
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase typically localized at focal adhesions, which are specialized multi-protein complexes that link the extracellular matrix (ECM) to the cytoplasmic cytoskeleton. Another component of the focal adhesions is tensin. This multi-domain protein may be involved in cell migration, fibrillar adhesion formation, cartilage development and in linking signal transduction pathways to the cytoskeleton. Tensin may also be an attractive target for potential renal disease, wound healing and cancer therapeutics strategies/research.
From a laboratory at University of Virginia.
These mouse IgG1 antibodies were generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing activated forms of pp60srC (pp6027F or pp602A/527F) and recognize chicken focal adhesion kinase (FAK).
Highlights:
- Reacts with chicken FAK
- May be useful for signal transduction pathways reserach, as well as oncogenic studies
- Suitable for Western Blot and Immunoprecipitation applications
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase typically localized at focal adhesions, which are specialized multi-protein complexes that link the extracellular matrix (ECM) to the cytoplasmic cytoskeleton. Another component of the focal adhesions is tensin. This multi-domain protein may be involved in cell migration, fibrillar adhesion formation, cartilage development and in linking signal transduction pathways to the cytoskeleton. Tensin may also be an attractive target for potential renal disease, wound healing and cancer therapeutics strategies/research.
From a laboratory at University of Virginia.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Name: | Anti-FAK [3C4] Antibody |
| Antigen: | p120/tensin |
| Accession ID: | Q05397 |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | 3C4 or 5B9 |
| Reactivity: | Chicken |
| Specificity: | Specific to chicken tensin |
| Immunogen: | Generated by immunizing mice with a mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing activated pp60src, and recognizes FAK |
| Species Immunized: | Mouse |
| Purification Method: | Protein A or A/G affinity purified |
| Buffer: | PBS, 0.05% Sodium Azide |
| Tested Applications: |
Clone 3C4: WB, IP; |
| Storage: | -20C |
| Shipped: | Cold packs |
- Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32. doi: 10.1073/pnas.87.9.3328. PMID: 2110361; PMCID: PMC53893.
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