Amyloid Beta Antibodies
![Anti-Amyloid Beta, aa 1-40 [P100] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/19_20210622134721205.jpg "Anti-Amyloid Beta, aa 1-40 [P100] Antibody")
These camelid (alpaca) IgG polyclonal antibodies were generated against brain homogenate derived from Alzheimer patient and recognize amyloid beta protein from human, mouse, and dog.
Highlights
- Shown to recognize amyloid beta protein from human, mouse, and dog
- Recommended for ELISA, Western blot, IHC, and IF applications
The progressive accumulation of extracellular amyloid plaques in the brain is a common hallmark of Alzheimer's disease. Forms of Amyloid beta phosphorylated at serine residue 8 have increased propensity to form toxic aggregates as compared to non-phosphorylated species.
From the laboratory of Mourad Tayebi, PhD, Western Sydney University.
These camelid (alpaca) IgG polyclonal antibodies were generated against brain homogenate derived from Alzheimer patient and recognize amyloid beta protein from human, mouse, and dog.
Highlights
- Shown to recognize amyloid beta protein from human, mouse, and dog
- Recommended for ELISA, Western blot, IHC, and IF applications
The progressive accumulation of extracellular amyloid plaques in the brain is a common hallmark of Alzheimer's disease. Forms of Amyloid beta phosphorylated at serine residue 8 have increased propensity to form toxic aggregates as compared to non-phosphorylated species.
From the laboratory of Mourad Tayebi, PhD, Western Sydney University.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
Specifications
| Product Type: | Antibody |
| Antigen: | Amyloid beta peptide 1-40 (P100), Amyloid beta peptide 1-42 (P200) |
| Accession ID: | P05067 |
| Molecular Weight: | 4329.82 Da (P100) 4514.1 Da (P200) |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Clone Name: | P100 |
| Reactivity: | human, mouse, dog |
| Immunogen: | Brain homogenate derived from Alzheimer patient |
| Species Immunized: | Alpaca |
| Method Used to Determine Concentration: | BCA |
| Buffer: | PBS |
| Tested Applications: | ELISA (1ug/mL), Western Blot (1ug/mL), IHC (1:500), IF (1:500) |
| Concentration: | 1mg/mL |
| Amount: | 100ug |
| Comments: | Brain homogenate adsorbed to immunomagnetic beads and emulsified in CFA and final booster in IFA.; References included refer to mAbs produced from the same animals the pAbs were derived from. |
| Storage: | -20C |
| Shipped: | Cold Packs |
Data
Western blot
Provider
From the laboratory of Mourad Tayebi, PhD, Western Sydney University.
References
- Rusbridge C, Salguero FJ, David MA, Faller KME, Bras JT, Guerreiro RJ, Richard-Londt AC, Grainger D, Head E, Brandner SGP, Summers B, Hardy J, Tayebi M. An Aged Canid with Behavioral Deficits Exhibits Blood and Cerebrospinal Fluid Amyloid Beta Oligomers. Front Aging Neurosci. 2018 Jan 30;10:7. doi: 10.3389/fnagi.2018.00007. PMID: 29441010; PMCID: PMC5797595.
- David MA, Jones DR, Tayebi M. Potential candidate camelid antibodies for the treatment of protein-misfolding diseases. J Neuroimmunol. 2014 Jul 15;272(1-2):76-85. doi: 10.1016/j.jneuroim.2014.05.001. Epub 2014 May 10. PMID: 24864011.
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