Norbelladine 4'-O-Methyltransferase (NpN4OMT)

Norbelladine 4'-O-Methyltransferase (NpN4OMT) from Narcissus sp. aff. pseudonarcissus is produced in E. coli BL21 (Rosetta) cells and purified by affinity chromatography using His-tag.

Norbelladine 4'-O-Methyltransferase (EC 2.1.1.336) is an enzyme involved in Amaryllidaceae alkaloid biosynthesis that utilizes the co-substrate S-adenosyl methionine to methylate norbelladine to form 4'-O-methylnorbelladine.

From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.

Catalog Number Product Size AVAILABILITY Price Qty
EDD008
Norbelladine 4'-O-Methyltransferase (NpN4OMT)
350ug In stock
Price: $250.00
Specifications
Product Type: Protein
Name: Norbelladine 4'-O-Methyltransferase
Accession ID: KJ584561
EC Number: EC 2.1.1.336
Source: E. coli BL21 (Rosetta)
Molecular Weight: 27,274 Da
Fusion Tag(s): His
Buffer: 50 mM potassium phosphate pH 8.0/ 10% glycerol
Comments: Requires S-adenosyl methionine as co-substrate
Storage: -80C
Shipped: Dry Ice
Provider
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
References
  1. Kilgore, M. B., M. M. Augustin, C. M. Starks, M. O'Neil-Johnson, G. D. May, J. A. Crow and T. M. Kutchan (2014). "Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus." PLoS One 9(7): e103223.

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