Norbelladine 4'-O-Methyltransferase (NpN4OMT)
Norbelladine 4'-O-Methyltransferase (NpN4OMT) from Narcissus sp. aff. pseudonarcissus is produced in E. coli BL21 (Rosetta) cells and purified by affinity chromatography using His-tag.
Norbelladine 4'-O-Methyltransferase (EC 2.1.1.336) is an enzyme involved in Amaryllidaceae alkaloid biosynthesis that utilizes the co-substrate S-adenosyl methionine to methylate norbelladine to form 4'-O-methylnorbelladine.
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
Norbelladine 4'-O-Methyltransferase (NpN4OMT) from Narcissus sp. aff. pseudonarcissus is produced in E. coli BL21 (Rosetta) cells and purified by affinity chromatography using His-tag.
Norbelladine 4'-O-Methyltransferase (EC 2.1.1.336) is an enzyme involved in Amaryllidaceae alkaloid biosynthesis that utilizes the co-substrate S-adenosyl methionine to methylate norbelladine to form 4'-O-methylnorbelladine.
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
Specifications
| Product Type: | Protein |
| Name: | Norbelladine 4'-O-Methyltransferase |
| Accession ID: | KJ584561 |
| EC Number: | EC 2.1.1.336 |
| Source: | E. coli BL21 (Rosetta) |
| Molecular Weight: | 27,274 Da |
| Fusion Tag(s): | His |
| Buffer: | 50 mM potassium phosphate pH 8.0/ 10% glycerol |
| Comments: | Requires S-adenosyl methionine as co-substrate |
| Storage: | -80C |
| Shipped: | Dry Ice |
Provider
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
References
- Kilgore, M. B., M. M. Augustin, C. M. Starks, M. O'Neil-Johnson, G. D. May, J. A. Crow and T. M. Kutchan (2014). "Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus." PLoS One 9(7): e103223.
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