Anti-Chikungunya virus (CHIKV) Antibodies

These mouse IgG2 monoclonal antibodies were raised against live Chikungunya virus (CHIKV) and recognize Chikungunya virus.

Highlights:

  • Reacts with Chikungunya virus (CHIKV)
  • Suitable for Western Blot and Immunofluorscence applications

Chikungunya virus (CHIKV) is known to be transmitted to humans by mosquito vectors, primarily Aedes aegypti and A. albopictus. Symptoms of chikungunya infection generally initiated 4-7 days after the bite of the mosquito vector and usually include high fever, asthenia, chills, headache, diarrhea, vomiting and rash. Myalgia and chronic, incapitating polyarthralgia is nevertheless the defining symptom of the disease, often persisting for weeks, months or even years. CHIKV gained its infamity from the severe outbreak in the Indian Ocean island of La Re'union in 2005-2006, in which 38.2% of the population was infected and 41.5 million people were documented to have experienced hemorrhagic fever manifestations. Unprecedentedly high fatality rates of one death per 1,000 infections were reported, along with atypical clinical manifestations such as severe dermatological lesions, lymphopenia, lethal hepatitis and encephalitis in predominantly susceptible individuals. Since the re-emergence of CHIKV in La Reunion, epidemic outbreaks of CHIKV infection have been reported globally and CHIKV is now considered endemic in 34 countries across Europe, Australia, Asia and Africa. Mouse monoclonal antibodies that are specific to chikungunya virus can be used as a research or diagnostic reagent to detect infection of cells.

From the laboratory of A*STAR Institute of Molecular and Cell Biology (IMCB) Monoclonal Antibody Unit.

Catalog Number Product Size AVAILABILITY Price Qty
ESG001
Anti-Chikungunya virus (CHIKV) [11E7] Antibody, 5mL (supernatant)
5mL supernatant 3-5 weeks
Price: $250.00
ESG002
Anti-Chikungunya virus (CHIKV) [6A11] Antibody, 5mL (supernatant)
5mL supernatant 3-5 weeks
Price: $250.00
Specifications
Product Type: Antibody
Antigen: Chikungunya virus (CHIKV)
Isotype: 11E7: IgG2a
6A11: IgG2b
Clonality: Monoclonal
Clone Name: 11E7
6A11
Reactivity: Chikungunya virus
Immunogen: Live Chikungunya virus
Species Immunized: Mouse
Buffer: Cell culture supernatant
Tested Applications: WB, IF
Storage: 80C
Shipped: Dry Ice
Data

Western Blot and Immunofluorescence

Figure (A) and (C): Western Blot analysis performed using cells infected with CHIKV (Inf) or mock infected (Mock). The 47kDa protein detected in the infected cells only is likely to be the E1 protein of CHIKV. MAb 11E7 was used for (A) and mAb 6A11 was used for (C). Figure (B) and (D): Immunostaining of cells infected with CHIKV (Inf) or mock infected (Mock) at 24 hours post-infection (hpi). MAb 11E7 was used for (B) and mAb 6A11 wasused for (D).

References

If you publish research with this product, please let us know so we can cite your paper.

 
Loading...
Loading...