Anti-EBV gp350 [HB5] Antibody
![Anti-EBV gp350 [HB5] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1695_2001202001265716940.jpg "Anti-EBV gp350 [HB5] Antibody")
This mouse IgG2a monoclonal antibody was raised against purified epstein-barr virus (EBV) and is specific for human EBV surface glycoprotein gp350.
Highlights:
- Recognizes human EBV gp350
- Works well for EBV neutralization
- Suitable for Western Blot, ELISA, Flow Cytometry, EBV in vitro Neutralization and Epitope Mapping applications
Epstein-Barr virus (EBV) infection is the causal agent of acute infectious mononucleosis and is associated with numerous epithelial and lymphoid malignancies, such as nasopharyngeal carcinoma, gastric carcinoma, Burkitt lymphoma, Hodgkin lymphoma, and post-transplant lymphoproliferative diseases (PTLD). EBV uses multiple surface glycoproteins (gps), including the major gp350, to infect host cells. EBV gp350 is a type 1 membrane protein that encodes for 907 amino acid (aa) residues and codes for a 350 kDa glycoprotein and a 220 kDa splice variant.
From the laboratory of Javier Gordon Ogembo, PhD, City of Hope.
This mouse IgG2a monoclonal antibody was raised against purified epstein-barr virus (EBV) and is specific for human EBV surface glycoprotein gp350.
Highlights:
- Recognizes human EBV gp350
- Works well for EBV neutralization
- Suitable for Western Blot, ELISA, Flow Cytometry, EBV in vitro Neutralization and Epitope Mapping applications
Epstein-Barr virus (EBV) infection is the causal agent of acute infectious mononucleosis and is associated with numerous epithelial and lymphoid malignancies, such as nasopharyngeal carcinoma, gastric carcinoma, Burkitt lymphoma, Hodgkin lymphoma, and post-transplant lymphoproliferative diseases (PTLD). EBV uses multiple surface glycoproteins (gps), including the major gp350, to infect host cells. EBV gp350 is a type 1 membrane protein that encodes for 907 amino acid (aa) residues and codes for a 350 kDa glycoprotein and a 220 kDa splice variant.
From the laboratory of Javier Gordon Ogembo, PhD, City of Hope.
| Product Type: | Antibody |
| Antigen: | EBV gp350 |
| Accession ID: | P03200 |
| Molecular Weight: | 350/220 kDa |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | HB5 |
| Reactivity: | Human |
| Immunogen: | Purified EBV |
| Species Immunized: | Mouse |
| Buffer: | 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB 1:50 (Unpurified Hybridoma supernatant), ELISA (10µg/ml), Flow cytometry (10µg/ml), EBV in vitro Neutralization (10-50µg/ml), Epitope Mapping (10µg/ml) |
| Storage: | -20C |
| Shipped: | Cold Packs |
- Mutsvunguma LZ, Rodriguez E, Escalante GM, Muniraju M, Williams JC, Warden C, Qin H, Wang J, Wu X, Barasa A, Mulama DH, Mwangi W, Ogembo JG. Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes. Virology. 2019 Jul 30;536:1-15. doi: 10.1016/j.virol.2019.07.026. [Epub ahead of print] PubMed PMID: 31377598.
If you publish research with this product, please let us know so we can cite your paper.
