Canine Osteosarcoma Cell Line (OSCA-29)

OSCA-29 is a canine osteosarcoma cell line derived from a primary tumor in the right front leg of a 6-year old female Rottweiler.

Highlights:

  • Gene expression profile is consistent with that observed in more aggressive molecular phenotype of osteosarcoma
  • Tumor also showed aggressive behavior in the original dog patient, eventually metastasizing to the brain

Osteosarcomas are aggressive malignant neoplasia that arise from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and exhibit osteoblastic differentiation and produce malignant osteoid.

From the laboratory of Jaime F. Modiano, VMD, PhD, University Minnesota, Twin Cities.

Catalog Number Product Size AVAILABILITY Price Qty
EMN014
Canine Osteosarcoma Cell Line (OSCA-29), 1 vial
1 vial 3-5 weeks
Price: $599.00
Specifications
Product Type: Cell Line
Name: OSCA-29
Cell Type: Osteosarcoma
Accession ID: CVCL_L384
Organism: Dog
Source: Bone (R. humerus)
Morphology: Spindle
Biosafety Level: 2
Growth Conditions: DMEM, 10% FBS, Doubling time approx. 1 day
Cryopreservation: 90%FBS/10% DMSO
Storage: -80C
Shipped: Dry Ice
Provider
From the laboratory of Jaime F. Modiano, VMD, PhD, University Minnesota, Twin Cities.
References
  1. Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 2011 Sep;49(3):356-67.

If you publish research with this product, please let us know so we can cite your paper.

 
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