7-Dehydrocholesterol-Epoxide
Oxidation product of 7-dehydrocholesterol.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Oxidation product of 7-dehydrocholesterol.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Specifications
| Product Type: | Small Molecule |
| Name: | 5α, 6α-epoxy-7-dehydrocholesterol |
| Chemical Formula: | C27H44O2 |
| Source: | synthetic |
| Molecular Weight: | 400.65 |
| Format: | white powder, shipped under an atmosphere of argon |
| Purity: | >95%, NMR |
| Solubility: | CHCl3, THF, benzene |
| Spectral Information: | 1H, 13C NMR |
| Comments: | susceptible to hydrolysis |
| Storage: | -80C |
| Shipped: | Dry ice |
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
- Korade Z, Genaro-Mattos TC, Tallman KA, Liu W, Garbett KA, Koczok K, Balogh I, Mirnics K, Porter NA. Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure. J Lipid Res. 2017 Sep 28. pii: jlr.M079475. View Article
- Wages PA, Kim HH, Korade Z, Porter NA. Identification and Characterization of Prescription Drugs that Change Levels of the Cholesterol Precursors 7 Dehydrocholesterol and Desmosterol. View Article
- Genaro-Mattos TC, Allen LB, Anderson A, Tallman KA, Porter NA, Korade Z, Mirnics K. Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment. Mol Psychiatry. 2019 Apr;24(4):491-500. View Article
If you publish research with this product, please let us know so we can cite your paper.
