Anti-PD-1 [J110] Antibody

This mouse IgG1 monoclonal antibody was generated against native programmed cell death protein 1 (PD-1) or cluster of differentiation 29 (C279) and is specific for PD-1.

Highlights:

  • Recognizes PD-1
  • Suitable for ELISA, Immunohistochemistry and Western Blot applications

PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells. PD-1 binds two ligands, PD-L1 and PD-L2. PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).

Catalog Number Product Size AVAILABILITY Price Qty
FCG010
Anti-PD-1 [J110] Antibody, 100ug
100ug In stock
Price: $380.00
Specifications
Product Type: Antibody
Antigen: Programmed cell death protein 1 (PD-1) and CD279 (cluster of differentiation 279)
Isotype: IgG1
Clonality: Monoclonal
Clone Name: J110
Immunogen: Native PD-1 protein
Species Immunized: Mouse
Purification Method: Protein G
Buffer: PBS, pH 7.2
Tested Applications: ELISA, WB, IHC, FFPE, IHC
Storage: -20C
Shipped: Cold packs
References

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