Anti-Hereditary Hemochromatosis Protein (HFE) Antibody
This rabbit IgG polyclonal antibody was raised against a 16 C-terminal amino acids based on the cDNA of the hereditary hemochromatosis protein (HFE) protein and is specific for human HFE.
Highlights:
- Recognizes human HFE
- Suitable for Western Blot, Immunoprecipitation and Immunohistochemistry applications
The HFE protein is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin. Mutations in the gene can cause an iron storage disorder called hereditary hemochromatosis (HCC), it results in excessive intestinal absorption of dietary iron resulting in a pathological increase in total body iron stores.
From the laboratory of Abdul Waheed, PhD, St. Louis University.
This rabbit IgG polyclonal antibody was raised against a 16 C-terminal amino acids based on the cDNA of the hereditary hemochromatosis protein (HFE) protein and is specific for human HFE.
Highlights:
- Recognizes human HFE
- Suitable for Western Blot, Immunoprecipitation and Immunohistochemistry applications
The HFE protein is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin. Mutations in the gene can cause an iron storage disorder called hereditary hemochromatosis (HCC), it results in excessive intestinal absorption of dietary iron resulting in a pathological increase in total body iron stores.
From the laboratory of Abdul Waheed, PhD, St. Louis University.
| Product Type: | Antibody |
| Accession ID: | Q30201 |
- Hannuksela, J., Parkkila, S., Waheed, A., Britton, R. S., Fleming, R. E., Bacon, B. R. and Sly, W. S. (2003), Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2. European Journal of Haematology, 70: 201206.
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