Brn2 (Inducible Tet-On) Lentivirus
This lentivirus expresses BRN2 under the control of the Tet promoter.
BRN2 (also known as POU3F2) encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
This lentivirus expresses BRN2 under the control of the Tet promoter.
BRN2 (also known as POU3F2) encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Virus |
| Product MPN: | PLV-10088-50 |
| Biosafety Level: | BSL-2 |
| Vector Information: | Vector includes both 5? and 3? lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Target Gene / Reporter(s): | Brn2 |
| Promoter: | TRE |
| Selection Gene: | Puromycin |
| Titer: | 1 x 10^8TU/mL |
| Storage: | Store at -80C. Multiple freeze/thaw cycles not recommended. |
| Shipped: | Dry ice |
NOTE: This Inducible Tet-On lentivirus does not contain the reverse tetracycline-controlled transactivator (rtTA) protein, which is required for the Tet-On system. Unless the cells used stably produce rtTA, it is necessary to cotransduce this lentivirus with a rtTA lentivirus (rtTA (CMV, neomycin) Lentivirus or rtTA (CMV, puromycin) Lentivirus.
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