Anti-BCH110/LSD1 Antibody
This rabbit IgG polyclonal antibody was generated against N terminus of BHC110 (first 20 amino acids) and is specific for human Lysine-specific histone demethylase 1A or BHC110/LDS1.
Highlights:
- Reacts with human BHC110/LDS1
- Recommended for Western Blot applications
BRAF35-HDAC complex protein BHC110, is a nuclear protein containing an amine oxidase domain, a SWIRM domain and a FAD-binding motif. BHC110 is included in some histone deacetylase complexes, but silences genes by functioning as a histone demethylase. Alternative splicing of BHC110 gene can produce multiple transcripts.
From the laboratories of Ramin Shiekhattar, PhD, The Wistar Institute.
This rabbit IgG polyclonal antibody was generated against N terminus of BHC110 (first 20 amino acids) and is specific for human Lysine-specific histone demethylase 1A or BHC110/LDS1.
Highlights:
- Reacts with human BHC110/LDS1
- Recommended for Western Blot applications
BRAF35-HDAC complex protein BHC110, is a nuclear protein containing an amine oxidase domain, a SWIRM domain and a FAD-binding motif. BHC110 is included in some histone deacetylase complexes, but silences genes by functioning as a histone demethylase. Alternative splicing of BHC110 gene can produce multiple transcripts.
From the laboratories of Ramin Shiekhattar, PhD, The Wistar Institute.
Specifications
| Product Type: | Antibody |
| Alternative Name(s): | Lysine-specific histone demethylase 1A or KDM1A |
| Antigen: | BHC110/LSD1 |
| Accession ID: | O60341 |
| Molecular Weight: | 100 kDa |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Reactivity: | Human |
| Immunogen: | N terminus of BHC110 (first 20aa) |
| Species Immunized: | Rabbit |
| Purification Method: | Affinity purified |
| Tested Applications: | Western Blot (1:1000) |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratories of Ramin Shiekhattar, PhD, The Wistar Institute.
References
- Hakimi MA, Bochar DA, Chenoweth J, Lane WS, Mandel G, Shiekhattar R. A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7420-5.
If you publish research with this product, please let us know so we can cite your paper.
