Alkynyl 7-Dehydrocholesterol
Alkynyl 7-dehydrocholesterol, the biosynthetic precursor to cholesterol, is a surrogate for the endogenous sterol. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Alkynyl 7-dehydrocholesterol, the biosynthetic precursor to cholesterol, is a surrogate for the endogenous sterol. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Specifications
| Product Type: | Small Molecule |
| Name: | Alkynyl 7-Dehydrocholesterol |
| Chemical Formula: | C26H38O |
| Molecular Weight: | 366.59 kDa |
| Format: | Solid |
| Purity: | >95%, NMR |
| Solubility: | CHCl3, THF, Benzene, DMSO |
| Spectral Information: | 1H, 13C NMR |
| Storage: | -20C |
| Shipped: | Ambient temperature |
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
- Windsor, K, Genaro-Mattos, TC, Kim, HY, Liu, W, Tallman, KA, Miyamoto, S, Korade Z, Porter, NA. Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome. J. Lipid Res. 2013, 54, 2842.
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