Alkynyl Iodoacetamide
The alkynyl iodoacetamide reacts with nucleophiles, such as cysteine in proteins and peptides. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
The alkynyl iodoacetamide reacts with nucleophiles, such as cysteine in proteins and peptides. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Specifications
| Product Type: | Small Molecule |
| Name: | Alkynyl iodoacetamide |
| Chemical Formula: | C5H6INO |
| Source: | Synthetic |
| Molecular Weight: | 223.01 kDa |
| Format: | Solid |
| Solubility: | DMSO, EtOH |
| Storage: | -20C |
| Shipped: | Ambient temperature |
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
- Petrova B, Liu K, Tian C, Kitaoka M, Freinkman E, Yang J, Orr-Weaver TL. Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes. Proc Natl Acad Sci U S A. 2018 Aug 6. View Article
- Tian C, Sun R, Liu K, Fu L, Liu X, Zhou W, Yang Y, Yang J. Multiplexed Thiol Reactivity Profiling for Target Discovery of Electrophilic Natural Products. Cell Chem Biol. 2017 Nov 16;24(11):1416-1427.e5. View Article
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