Alkynyl 4-oxo-2-nonenal (aONE)
Alkynyl ONE is a surrogate for endogenously generated ONE, a product of lipid oxidation and indicator or oxidative stress. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Alkynyl ONE is a surrogate for endogenously generated ONE, a product of lipid oxidation and indicator or oxidative stress. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
Specifications
| Product Type: | Small Molecule |
| Name: | Alkynyl 4-oxo-2-nonenal (aONE) |
| Chemical Formula: | C9H10O2 |
| Source: | Synthetic |
| Molecular Weight: | 150.17 kDa |
| Format: | Solid |
| Solubility: | DMSO, EtOH |
| Storage: | -20C |
| Shipped: | Ambient temperature |
Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
- Codreanu, SG, Ullery, JC, Zhu, J, Tallman, KA, Beavers, WN, Porter, NA, Marnett, LJ, Zhang, B, Liebler, DC. Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems. Mol. Cell. Proteomics 2014, 13, 849.
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