Anti-GRIM-19 [1A8] Antibody
![Anti-GRIM-19 [1A8] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/881_200120200126258800.jpg "Anti-GRIM-19 [1A8] Antibody")
This IgG2a mouse monoclonal (clone 1A8) was generated against recombinant human Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19), and recognizes human and mouse GRIM-19.
Highlights:
- Recognizes human and mouse GRIM-19
- Recommended for WB, IP, IHC, IF, and ELISA applications
GRIM-19, otherwise known as designated cell death-regulatory protein GRIM 19 and NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13, is known to play a role in programmed cell death (apoptosis) and the electron transport chain. GRIM19 is widely expressed within tissues, including heart, skeletal muscle, liver, kidney and placenta. Mutations in GRIM-19 have been associated with Hurthle cell thyroid carcinoma (HCTC), a rare type of thyroid cancer.
From the laboratory of Dhan V. Kalvakolanu, PhD, University of Maryland, Baltimore.
Part of The Investigator's Annexe program.
This IgG2a mouse monoclonal (clone 1A8) was generated against recombinant human Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19), and recognizes human and mouse GRIM-19.
Highlights:
- Recognizes human and mouse GRIM-19
- Recommended for WB, IP, IHC, IF, and ELISA applications
GRIM-19, otherwise known as designated cell death-regulatory protein GRIM 19 and NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13, is known to play a role in programmed cell death (apoptosis) and the electron transport chain. GRIM19 is widely expressed within tissues, including heart, skeletal muscle, liver, kidney and placenta. Mutations in GRIM-19 have been associated with Hurthle cell thyroid carcinoma (HCTC), a rare type of thyroid cancer.
From the laboratory of Dhan V. Kalvakolanu, PhD, University of Maryland, Baltimore.
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Accession ID: | 51079 |
| Antigen: | Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19) |
| Molecular Weight: | 16 kDa |
| Isotype: | IgG2a |
| Clonality: | Monoclonal |
| Clone Name: | 1A8 |
| Reactivity: | Human and mouse |
| Immunogen: | Recombinant human GRIM-19 |
| Species Immunized: | Mouse |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, IP (1:200), IHC, IF (1:1000), ELISA (1:200,000) |
| Storage: | -20C |
| Shipped: | Cold packs |
- Hu J, Angell JE, Zhang J, Ma X, Seo T, Raha A, Hayashi J, Choe J, Kalvakolanu DV. Characterization of monoclonal antibodies against GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death. J. Interferon Cytokine Res. 2002 Nov;22(11):1150.
If you publish research with this product, please let us know so we can cite your paper.
