Anti-ADAM28 (mouse), Extracellular Domain Antibody

This rabbit IgG polyclonal antibody was generated against the entire ectodomain of ADAM28 including the EGF repeat fused to the Fc domain of human IgG and is specific for the extracellular domain of mouse ADAM28.

The ADAM (A Disintegrin And Metalloprotease Domain) family is a unique group of proteins that has the ability to cleave or shed extracellular portions of transmembrane proteins. In addition, ADAMs are involved in cell-cell and cell-matrix interactions (e.g., fertilization, muscle development and neurogenesis).

Based on sequence identity, ADAM28 is more closely related to snake venom metalloproteases (SVMPs) than to presently known ADAMs. Northern blot analysis revealed ADAM28 is expressed in the epididymis, suggesting a possible role in sperm maturation, and in the lung. Mature ADAM28 is presumed to be catalytically active and found mainly on the cell surface.

From the laboratory of Carl P. Blobel, MD, PhD, Hospital for Special Surgery.

Catalog Number Product Size AVAILABILITY Price Qty
EHS012
Anti-ADAM28 (mouse), Extracellular Domain Antibody, 100uL
100uL In stock
Price: $299.00
Specifications
Product Type: Antibody
Accession ID: AF153350
Antigen: GST-ADAM28 Cytoplasmic Domain
Molecular Weight: ~100 kDa
Isotype: IgG
Clonality: Polyclonal
Reactivity: Mouse
Immunogen: Entire ectodomain of mouse ADAM28 including the EGF repeat fused to the Fc domain of human IgG1
Species Immunized: Rabbit
Epitope: Extracellular domain
Purification Method: Serum, not purified
Tested Applications: WB (1:500), only on non-reduced samples (no DTT or BME)
Storage: -80C
Shipped: Dry ice
Research
Antibody Species Reactivity Specificity
ADAM9 Human Cytoplasmic Domain
ADAM9 Mouse Cytoplasmic Domain
ADAM12 Mouse Cytoplasmic Domain
ADAM15 Human Cytoplasmic Domain
ADAM15 Mouse Cytoplasmic Domain
ADAM15 Human Extracellular Domain
ADAM15 Mouse Disintegrin Domain
ADAM17 Mouse Cytoplasmic Domain
ADAM17 Mouse Pro domain
ADAM19 Mouse Cytoplasmic Domain
ADAM28 Mouse Cytoplasmic Domain
ADAM28 Mouse Extracellular Domain
SNX9 Mouse Cytoplasmic Domain
Provider
From the laboratory of Carl P. Blobel, MD, PhD, Hospital for Special Surgery.
References
  1. Howard, L.; Zheng, Y.; Horrocks, M.; Maciewicz, R. A.; Blobel, C. Catalytic activity of ADAM28. FEBS Lett. 2001, 498, 82-86.

If you publish research with this product, please let us know so we can cite your paper.

 
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