This mouse IgG monoclonal antibody was generated against whole Rat PITPb protein and recognizes Human, Mouse, Rat and Dog PITPb. This antibody is specific for both splice variants of PITPß but does not recognise PITPa despite the 95% similarity between the two.
Mammalian PITPß (phosphatidylinositol transfer protein ß) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITPß is embryonically lethal.
From a laboratory at Cancer Research Technology.
Part of The Investigator's Annexe program.
|Reactivity:||Human, Mouse, Rat and Dog|
|Immunogen:||Whole Rat PITPb protein|
|Tested Applications:||ELISA IF WB|
|Comments:||Antibody specific for both splice variants of PITPb but does not recognise PITPa. Does work in IF but not as good as DaRT/U/4a7|
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