This mouse IgG2a monoclonal antibody was generated against a recombinant His-tagged protein fragment of Human BCLAF1 and recognizes human BCL2 Associated Transcription Factor 1 (BCLAF1).
BCL2-associated transcription factor 1 (BCLAF1), also known as BTF, is a 920 amino acid protein that localizes to both the nucleus and the cytoplasm. Overexpression of BCLAF1 promotes apoptosis by preventing the transcription of Bcl-2. Bcl-2 is one of many key regulators of apoptosis which are essential for development, tissue homeostasis and protection against foreign pathogens. Four isoforms of BCLAF1 exist due to alternative splicing events.
From a laboratory at Cancer Research Technology.
Part of The Investigator's Annexe program.
|Antigen:||BCL2 Associated Transcription Factor 1 (BCLAF1)|
|Immunogen:||Recombinant His-tagged protein fragment of Human BCLAF1|
|Tested Applications:||IP WB|
|Comments:||Suggested Dilution for western blot: 1:3000|
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