This affinity purified antibody was raised in rabbits against the p400 C-terminal peptide (SSDSPSQQPKLQMRVPAVRLKTPTKPP) and is recommended for detection of human p400 by Western blot.
E1A-binding protein p400 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. p400 belongs to the SWI2/SNF2 family of ATPases and is found in two highly related chromatin remodelling complexes : the Tip60 and p400 complexes. It has been implicated in cell cycle control, apoptosis and development.
From the laboratory of John Chrivia, PhD, St. Louis University.
Part of The Investigator's Annexe program.
|Antigen:||p400 (human domino ortholog)|
|Molecular Weight:||400 kDa|
|Reactivity:||Human (use with other species has not been tested)|
|Purification Method:||Affinity purified using anti-peptide column|
|Tested Applications:||WB (1:1000)|
|Concentration:||1 mg/mL, (Bradford assay)|
If you publish research with this product, please let us know so we can cite your paper.