This antibody is specific to a Human NPC1 fragment conjugated to a carrier protein.
Niemann-Pick disease type C1 is a lysosomal storage disease caused by a mutation in the NPC1 gene. NPC1 encodes an integral membrane protein containing sequence motifs thought to be consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations. Mutations in NPC1 have also been linked with obesity, HIV-AIDS, and Ebola virus.
From the laboratory of Yiannis Ioannou, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
|Name:||Anti NPC1 monoclonal antibody (17B5)|
|Specificity:||This antibody recognizes Human NPC1|
|Immunogen:||Human NPC-1 fragment conjugated to a carrier protein|
|Purification Method:||Protein G purified|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Storage:||Store at 4C|
If you publish research with this product, please let us know so we can cite your paper.