Anti-Arginine-Gingipain B (RgpB) [18E6] Antibody
![Anti-Arginine-Gingipain B (RgpB) [18E6] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-Arginine-Gingipain B (RgpB) [18E6] Antibody")
This mouse IgG1 monoclonal anitbody was raised against protein and recognzies Porphyromonas gingivalis arginine-gingipain B (RgpB).
Highlights:
- Reacts with p. gingivalis RgpB
- Suitable for Immunoprecipitation and Immunofluorescence applications
Porphyromonas gingivalis is an oral pathogen that can induce periodontal disease. RgbP has also been detected in the brains of Alzheimer's disease patients with levels correlating with disease markers.
From a laboratory at University of Georgia..
This mouse IgG1 monoclonal anitbody was raised against protein and recognzies Porphyromonas gingivalis arginine-gingipain B (RgpB).
Highlights:
- Reacts with p. gingivalis RgpB
- Suitable for Immunoprecipitation and Immunofluorescence applications
Porphyromonas gingivalis is an oral pathogen that can induce periodontal disease. RgbP has also been detected in the brains of Alzheimer's disease patients with levels correlating with disease markers.
From a laboratory at University of Georgia..
Specifications
| Product Type: | Antibody |
| Accession ID: | CPG2_PORGI |
| Antigen: | Arginine-gingipain B |
| Molecular Weight: | 485 kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | 18 E6 |
| Immunogen: | Protein |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | IP, IF |
| Storage: | -20C |
| Shipped: | Cold Packs |
Provider
From a laboratory at University of Georgia.
References
- Nguyen KA, Travis J, Potempa J. Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria?. J Bacteriol. 2007;189(3):833-843. doi:10.1128/JB.01530-06.
- Dominy SS, Lynch C, Ermini F, et al. Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Sci Adv. 2019;5(1):eaau3333. Published 2019 Jan 23.
- Pomowski A, Usón I, Nowakowska Z, et al. Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome. J Biol Chem. 2017;292(14):5724-5735.
- Potempa J, Pike R, Travis J. The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain. Infect Immun. 1995;63(4):1176-1182.
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